Mutations in the ATP8B1 gene cause two autosomal recessive disorders affecting liver: cholestasis, benign recurrent intrahepatic, 1 (BRIC1), cholestasis, progressive familial intrahepatic, 1 (PFIC1) and one autosomal dominant disorder: cholestasis, intrahepatic, of pregnancy, 1 (ICP1). BRIC2 is caused by mutations in the ABCB11 gene.read more

Tests Available

By gene: ABCB4
Next Generation Sequencing
$990
Test Code: 2256
Deletion / Duplication
$680
Test Code: 2257
NGS/Del Dup Comprehensive
$1,570
Test Code: 2258

Related Panels
Cholestasis NGS Panel (4 genes)
NGS $1,240
Del Dup $850
Comp $1,990

Test Details

Technical Information
Genes: 
ABCB4
Disease Groups: 
Liver Disorders
MIM: 
602347
Billing
Price: 
$990
CPT Codes: 
81479 x 1
Ordering
SKU:
2256
Turnaround Time: 
Typically 2 to 4 weeks from receipt of a sample in the laboratory. All cases involving ongoing pregnancies will be expedited.
Non-Prenatal Specimens: 
  1. Whole blood: purple-top (EDTA) tube, minimum of 3 ml
  2. Genomic DNA: a minimum of 3 µg (at a concentration of at least 30 ng/µl)
  3. Fibroblasts: 4 confluent T-25 flasks
  4. Saliva: only samples collected in Oragene DNA Self-Collection Kit or Oragene Saliva Collection Kit for Young Children are accepted
Prenatal Specimens: 
  1. Cultured cells: 4 confluent T-25 flasks derived from amnio or CVS samples
  2. Genomic DNA: a minimum of 3 µg (at a concentration of at least 30 ng/µl)
Shipping: 
Ship all specimen types at room temperature by overnight courier. Do not freeze.

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