Mitral valve prolapse (MVP) is a common finding with a prevalence of approximately 2 to 3% in the general population.  It is characterized by fibromyxomatous changes in mitral leaflet tissue, with upward displacement of one or both leaflets into the left atrium during systole. MVP2 (MIM 607829) is nonsyndromic and it has been shown to be caused by autosomal dominant mutations in the DCHS1 gene encoding protocadherin-16.read more

Tests Available

By gene: DCHS1
Next Generation Sequencing
$990
Test Code: 2345
Deletion / Duplication
$680
Test Code: 2346
NGS/Del Dup Comprehensive
$1,570
Test Code: 2347

Test Details

Technical Information
Genes: 
DCHS1
Disease Groups: 
Craniosynostosis and Craniofacial Disorders
Neurological and Muscular Disorders
Skeletal Dysplasias
Billing
Price: 
$990
CPT Codes: 
81479 x 1
Ordering
SKU:
2345
Turnaround Time: 
Typically 3 to 4 weeks from receipt of a sample in the laboratory. All cases involving ongoing pregnancies will be expedited.
Non-Prenatal Specimens: 
  1. Whole blood: purple-top (EDTA) tube, minimum of 3 ml
  2. Genomic DNA: minimum of 10 µg (at a concentration of at least 50 ng/µl)
  3. Fibroblasts: 4 confluent T-25 flasks
  4. Saliva: only samples collected in Oragene DNA Self-Collection Kit or Oragene Saliva Collection Kit for Young Children are accepted
Prenatal Specimens: 
  1. Cultured cells: 4 confluent T-25 flasks derived from amnio or CVS samples
  2. Genomic DNA: minimum of 10 µg (at a concentration of at least 50 ng/µl)
Shipping: 
Ship all specimen types at room temperature by overnight courier. Do not freeze.

Search Tests

TIP: enter a partial disorder name or gene to widen your search