Number of Panel Genes: 
16

Heritable dental developmental anomalies include amelogenesis imperfecta (AI), dentinogenesis imperfecta (DI), and dentin dysplasia (DD).  AI, also called congenital enamel hypoplasia, is an inherited defect of dental enamel formation. The teeth are small, discolored, pitted or grooved, and prone to rapid wear and breakage. It affects all or nearly all of the teeth in both the primary and permanent dentitions. DI is a hereditary disorder of dentin formation.read more

Tests Available

16 Panel Genes: AMELX, C4ORF26, DLX3, DSPP, ENAM, FAM20A, FAM83H, GPR68, ITGB6, KLK4, LAMA3, LAMB3, MMP20, SLC24A4, SMOC2, WDR72
Next Generation Sequencing
$1,570
Test Code: 5197
Partial coverage for DSPP exon 5.
Deletion / Duplication
$1,150
Test Code: 5198
Del / Dup not available for FAM83H. WDR72 exon 18 not covered. Partial coverage for DSPP exon 5.
NGS/Del Dup Comprehensive
$2,570
Test Code: 5199
Del / Dup not available for FAM83H. WDR72 exon 18 not covered. Partial coverage for DSPP exon 5.

Test Details

Technical Information
Panel Genes: 
AMELX, C4ORF26, DLX3, DSPP, ENAM, FAM20A, FAM83H, GPR68, ITGB6, KLK4, LAMA3, LAMB3, MMP20, SLC24A4, SMOC2, WDR72
Test Note: 
Partial coverage for DSPP exon 5.
Disease Groups: 
Skin, Tooth, Nail and Hair Disorders
Billing
Price: 
$1,570
CPT Codes: 
81479 x 16
Ordering
SKU:
5197
Turnaround Time: 
Typically 3 to 4 weeks from receipt of a sample in the laboratory. All cases involving ongoing pregnancies will be expedited.
Non-Prenatal Specimens: 
  1. Whole blood: purple-top (EDTA) tube, minimum of 3 ml
  2. Genomic DNA: minimum of 10 µg (at a concentration of at least 50 ng/µl)
  3. Fibroblasts: 4 confluent T-25 flasks
  4. Saliva: only samples collected in Oragene DNA Self-Collection Kit or Oragene Saliva Collection Kit for Young Children are accepted
Prenatal Specimens: 
  1. Cultured cells: 4 confluent T-25 flasks derived from amnio or CVS samples
  2. Genomic DNA: minimum of 10 µg (at a concentration of at least 50 ng/µl)
Shipping: 
Ship all specimen types at room temperature by overnight courier. Do not freeze.

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