Number of Panel Genes: 
24

Amyotrophic lateral sclerosis (ALS) is a fatal, progressive, adult onset neurodegenerative disorder characterized by degeneration of both upper and lower motor neurons. The main symptoms include muscle fasciculations, cramps, weakness and wasting, muscle spasticity, slurred or nasal speech, and difficulties in chewing or swallowing.  ALS can be sporadic or familial. The mean age of onset for sporadic and familial ALS is approximately 56 and 46 years old, respectively.read more

Tests Available

24 Panel Genes: ALS2, ANG, ARHGEF28, CHCHD10, CHMP2B, ERBB4, FIG4, FUS, HNRNPA1, HNRNPA2B1, MATR3, OPTN, PFN1, SETX, SIGMAR1, SOD1, SPG11, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP
Next Generation Sequencing
$1,470
Test Code: 5235
Deletion / Duplication
$990
Test Code: 5236
NGS/Del Dup Comprehensive
$1,845
Test Code: 5237

Test Details

Technical Information
Panel Genes: 
ALS2, ANG, ARHGEF28, CHCHD10, CHMP2B, ERBB4, FIG4, FUS, HNRNPA1, HNRNPA2B1, MATR3, OPTN, PFN1, SETX, SIGMAR1, SOD1, SPG11, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP
Disease Groups: 
Neurological and Muscular Disorders
Billing
Price: 
$1,470
CPT Codes: 
81403 x 1
81404 x 1
81405 x 1
81406 x 4
81407 x 1
81479 x 16
Ordering
SKU:
5235
Turnaround Time: 
Typically 2 to 4 weeks from receipt of a sample in the laboratory. All cases involving ongoing pregnancies will be expedited.
Non-Prenatal Specimens: 
  1. Whole blood: purple-top (EDTA) tube, minimum of 3 ml
  2. Genomic DNA: a minimum of 3 µg (at a concentration of at least 30 ng/µl)
  3. Fibroblasts: 4 confluent T-25 flasks
  4. Saliva: only samples collected in Oragene DNA Self-Collection Kit or Oragene Saliva Collection Kit for Young Children are accepted
Prenatal Specimens: 
  1. Cultured cells: 4 confluent T-25 flasks derived from amnio or CVS samples
  2. Genomic DNA: a minimum of 3 µg (at a concentration of at least 30 ng/µl)
Shipping: 
Ship all specimen types at room temperature by overnight courier. Do not freeze.

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